Possibility of correction of functional disorders with pectin substances central nervous system under conditions of methanol intoxication. Experimental research
AUTHORS : Chervonnaya N.M. | Adzhiakhmetova S.L. | Pozdnyakov D.I. | Oganesyan E.T. | Larsky M.V.
RELEVANT UNIVERSITIES : Pyatigorsk Medical and Pharmaceutical Institute – branch of the Volgograd
State Medical University of the Ministry of Health of Russia (Pyatigorsk)
YEAR : 2021
SUMMARY The article presents the results of a study on the effect of pectin substances obtained from the inflorescences of Gaillardia pulchella Foug; inflorescences of Tagetes patula L; herbs Sorbaria sorbifolia L; leaves Ribes nigrum L; leaves of Grossularia reclinata L; leaves of Lysimachia punctata L., on the change in neurological and sensorimotor deficits, as well as the functional activity of brain mitochondria in rats against the background of acute methanol intoxication. The results obtained indicate that the introduction of all studied pectin substances at a dose of 100 mg / kg (per os) reduced neurological and sensorimotor disorders in animals
and restored the reactions of energy metabolism in the brain tissue,