Study of anti-inflammatory and analgesic activity compass lettuce herb (Lactuca serriola L.)
AUTHORS : Artyushkova E. B. | Gladchenko M.P. | Korableva T.V. | Bubenchikov R.A.
RELEVANT UNIVERSITIES : FSBEI HE “Kursk State Medical University” of the Ministry of Health of Russia (Kursk)
YEAR : 2020
SUMMARY The article presents the results of a study of acute toxicity, anti-inflammatory and analgesic activity of compass lettuce herb. It was found that a single infusion of the infusion in doses from 1 g / kg to 5 g / kg made it possible to classify it as practically non-toxic. Anti-inflammatory activity was studied in a model of acute inflammation of the foot of mice caused by subplantar
administration of 0.1 ml of 1% carrageenan solution. The antiexudative activity of the infusion was 17.5%. The analgesic activity of the infusion was studied on the model of chemical pain irritation (“cramps”) caused by the administration of acetic acid in mice. It was found that the analgesic effect was 27.1%.