Newt regeneration signal
AUTHORS : Chayanovone N.V. | Bizyaevone P.D. | Burlakovaone O.V. | Golichenkovone V.A. | Gotovsky2 M.Yu. | Mkhitaryan2 K.N.
RELEVANT UNIVERSITIES : oneDepartment of Embryology, Biological Faculty, Moscow State University, 2Center “IMEDIS”, Moscow, Russia
YEAR : 2008
Introduction Tailed amphibians (newts, amblystomas) are the only vertebrates in which complete true regeneration of limbs occurs.
Materials and methods The idea was to “record” the control signal (CS) corresponding to different stages of restoration of the lost limb: immediately after the injury, the next day (the beginning of the epithelialization of the stump), after 2 days – the completion of the epithelialization of the stump, then 1 or 2 times per week to fix the various stages of osteoporosis (the remainder of the bone is absorbed) and, in fact,
regeneration.