Anti-opisthorchiasis activity of plants of the genus Achillea and genus Artemisia: research results in conditions in vitro and in vivo
AUTHORS : Kaminsky I.P. | Kadyrov T.V. | Ivanov V.V. | Osadchiy A.G. Miroshnichenko A.G. | Belousov M.V.
RELEVANT UNIVERSITIES : Federal State Budgetary Educational Institution of Higher Education “Siberian State Medical University” of the Ministry of Health of the Russian Federation (Tomsk)
YEAR : 2019
Carried out screening pharmacological studies of plants of the genus Achillea (yarrow: Achillea millefolium L. – t. common, Achillea nobilis L. – t. noble) and Artemisia (wormwood:
Artemisia absinthium L. – n. bitter, Artemisia vulgaris L. – n. ordinary, Artemisia gmelinii Web.ex
Stechm – n. Gmelin, Artemisia dracunculus L. – n. Tarragon) of the family Asteraceae – Astrovye. The
presence of a group of sesquiterpene lactones (as a potential carrier of anthelmintic activity against
Opisthorchis felineus) in all studied plant objects was confirmed. The specific anti-opisthorchiasis
activity of the fractions of sesquiterpene lactones of plants of the genera Yarrow and Wormwood has
been studied using an in vitro model, and the most promising objects have been identified.