Pathophysiological analysis of the effect of GA-40 and the antioxidant ionol on liver biochemical parameters in acute hemic hypoxia in the study of rat liver fragments using the vegetative resonance test “IMEDISTEST +”
AUTHORS : Rogovy Yu.E. | Arkhipova L.G. | Muravyova I.L. | Popovich A.B.
RELEVANT UNIVERSITIES : Department of Physiology, Bukovina State Medical University,
CHOMDTS, Chernivtsi, Ukraine
YEAR : 2007
The aim of the study was to conduct a pathophysiological analysis of the effect of GA40 and the antioxidant ionol on the biochemical parameters of rat liver in acute hemic
hypoxia using the vegetative resonance test “IMEDIS-TEST +”. In experiments on 24 sexually mature white male rats with acute hemic hypoxia of moderate severity (administration of 1% sodium nitrite solution subcutaneously at a dose of 50 mg / kg once), the protective effect of GA-40 was studied [4, 5]
(injected intramuscularly at a dose of 2 μg / kg body weight) and antioxidant ionol (injected intraperitoneally at a dose of
120 mg / kg body weight) using the vegetative resonance test “IMEDIS-TEST +” [1, 2, 3]. The GA-40 preparation and the
antioxidant ionol in acute hemic hypoxia increased the content in the liver: