Investigation of the informativeness of the vegetative resonance test in dianosis of diseases of the inner ear and idiosyncrasy to aminoglycosides.
AUTHORS : Abakarov M.G.| Magomedov M.M.| Makayev H.M.| Khanakaeva Z.K.
RELEVANT UNIVERSITIES : Department of Clinical
Famacology, Federal State Institution of Higher Professional Education “Russian State Medical
University” of Roszdrav, Head Professor, Corresponding Member of RAMNYU.B.Belousov;
Department of Otolaryngology, Federal State Institution of Higher Professional Education “Russian State Medical
University” of Roszdrav, Head Professor, Corresponding Member of RAMS VT Palchun; ENT department of the
Federal State Institution “Moscow Research Institute of Pediatrics and Pediatric Surgery”; Moscow city,
Russia
YEAR : 2007
Currently, a large number of drugs are known that can cause damage to the auditory analyzer with a frequent outcome in irreversible sensorineural hearing
loss. The most studied drug sensorineural hearing loss caused by aminoglycosides, which, in accordance with modern concepts, develops by the mechanism of
idiosyncrasy as a result of genetic mutations, and drugs cause the phenotypic manifestation of these mutations (Fishel-Gotsian, 1998). After the identification of
the A1555G mutation in the 12S position of mitochondrial RNA in the United States, the issue of molecular genetic screening began to be discussed