Hepatoprotective activity of a complex plant extract
AUTHORS : Ferubkoone E.V. | Nikolaev2 CM. | Pupykina3 K.A. | Dargaevaone Etc.
RELEVANT UNIVERSITIES : oneFSBSI “All-Russian Research Institute medicinal and aromatic plants, Moscow; 2 FSBSI “Institute of General and Experimental Biology” Siberian Branch of the Russian Academy of Sciences, Ulan-Ude; 3 FSBEI HE “Bashkir State Medical University” of the Ministry of Health of the Russian Federation, Ufa
YEAR : 2018
SUMMARY The article presents the results of a study of the hepatoprotective activity of a complex plant extract obtained from the following types of plant materials: roots and rhizomes of elecampane high, herb of centaury, Ural licorice roots, rose hips, hawthorn fruits, under the conditions of a model of tetrachloromethane hepatitis. It was found that the course administration of per os extract at a dose of 300 mg / kg to white nonlinear rats
with carbon tetrachloride damage to the liver has a hepatoprotective effect, to some extent surpassing the
effect of the comparison drug Carsil. The results of the studies showed that during the pharmacotherapy of toxic
hepatitis with a plant extract, the levels of activity of enzymes – markers of the cytolysis syndrome, clearly
decrease in the blood serum, Significantly decrease in these conditions and manifestations of cholestasis
syndrome.
