Comparative evaluation of antidiabetic properties of decoctions from Caragana Lam species
AUTHORS : Barnaulov1 O.D. | Belodubrovskaya2 G.A.
RELEVANT UNIVERSITIES : 1Institute of the Human Brain. N.P. Bekhtereva RAS,2Saint Petersburg State
Chemical and Pharmaceutical University of the Ministry of Health of the Russian Federation, St. Petersburg
YEAR : 2019
SUMMARY On a model of alloxan diabetes in rats and mice, a primary screening comparative assessment of the
antidiabetic activity of decoctions of deciduous branches of 17 species of Caragana of the legume family was given. An antihyperglycemic effect, an increase in the level of insulin and C-pepstide against the background of treatment with decoctions of most of the studied species, comparable to those of control drugs (butamide,
blueberry shoots, ginseng leaves), has been proven. According to the total index of antidiabetic activity, 10 out
of 17 species deserve further, more in-depth study.