Antioxidant activity of some herbal extracts genus Chernogolovka (Prunella L.): in vitro and in vivo research
AUTHORS : Shamilov1 A.A. | Pozdnyakov1 D.I. | Bubenchikova2 V.N. | Chernikov1 M.V. Garcia1 E.R.
RELEVANT UNIVERSITIES : 1PMFI – branch of the Volgograd State Medical University of the Ministry of Health of Russia (Pyatigorsk),
2FSBEI HE “Kursk State Medical University” of the Ministry of Health of Russia (Kursk)
YEAR : 2020
SUMMARY The article presents the results of an experimental study devoted to in vitro and in vivo assessment
of the antioxidant activity of aqueous and aqueous-alcoholic extracts obtained from the herb of three
representatives of the genus Prunella L .: Prunella grandiflora L., Prunella laciniata L. and Prunella vulgaris
L. As a result, it was It was found that the highest antioxidant potential is possessed by the dry residues of
water-alcohol extracts (extractant: ethyl alcohol 70%), which, when introduced into the model medium,
most significantly inhibited the formation of superoxide, hydroxyl and DPPH radicals, and also improved
the pro / antioxidant balance in animals without a pathological background
