Controversial acute toxicity of Saussurea dry extract

Controversial acute toxicity of Saussurea dry extract

AUTHORS :  Avdeeva Yu. | Reshetov Ya. E. | Gulina E.I. | Miroshnichenko A.G. | Belousov M.V.

RELEVANT UNIVERSITIES : Federal State Budgetary Educational Institution of Higher Education “Siberian State Medical University” of the Ministry of Health of the Russian Federation (Tomsk)
YEAR : 2019


SUMMARY Determined the acute toxicity of dry extract of controversial saussurea (Saussurea controversa DC.), Which has osteogenic, immunomodulatory and anti-inflammatory activity. According to the results of toxicometry, observations of experimental animals for 14 days after acute administration and necropsy data, the studied extract according to the classification of  Hodge and Sterner belongs to low-toxic substances, and according to GOST 12.1.007-76 – to low-hazard substances (IV hazard class), which along with its high biological activity, it provides a prospect for its further study and implementation in medical practice.



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