The choice of the optimal technology of the controversial Saussurea extract, which stimulates the hematopoietic function of the bone marrow, having osteogenic and immunotropic activity
AUTHORS : Avdeeva E.Yu. | Reshetov Ya. E. | Gulina E.I. | Belousov M.V.
RELEVANT UNIVERSITIES : Federal State Budgetary Educational Institution of Higher Education “Siberian State Medical University” of the Ministry of Health of the Russian Federation (Tomsk)
YEAR : 2019
SUMMARY Extract of leaves of controversial saussurea (Saussurea controversa DC.) Exhibits osteogenic, immunomodulatory, anti-inflammatory activity and is a promising candidate for expanding the arsenal of means of complex conservative therapy of osteomyelitis. As a result of the study, the optimal parameters for the extraction of target components (flavonoids,
chelidonic acid, minerals) of the controversial Saussurea extract were revealed. The optimal conditions for the extraction with 40% aqueous ethanol was a threefold extraction of leaves of a plant, crushed to 3–6 mm, in a ratio of 1:15 at 80 ° С for 60 min.
