Development of technology for the manufacture of capsules of madder dyeing

Development of technology for the manufacture of capsules of madder dyeing

AUTHORS :  Rybalko1 M.V. | Kurkin2 V.A. | Shmygareva1 A.A. | Sankov1 A.N.

RELEVANT UNIVERSITIES : 1 Federal State Budgetary Educational Institution of Higher Education “Orenburg State Medical University” of the Ministry of Health of the Russian Federation (Orenburg),
2FSBEI HE “Samara State Medical University” of the Ministry of Health of the Russian Federation (Samara)
YEAR : 2019

 

SUMMARY A new method of obtaining an extract of madder (Rubia tinctorum L.) using the method of modified maceration and ultrasound for the production of a dosage form – a capsule is described. When using this method, the maximum yield of anthracene derivatives from raw materials is observed, while the content of the sum of anthracene derivatives in the capsule in terms of ruberitric
acid is 8.5 mg. The use of madder dye extract in encapsulated form (with the introduction of indifferent excipients into the composition) allows to reduce the frequency of taking the drug, and to use this drug for people suffering from diabetes mellitus.

 

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