Anti-opisthorchiasis activity some species of the genus Cornflower (Centaurea) of the flora of Western Siberia

Anti-opisthorchiasis activity some species of the genus Cornflower (Centaurea) of the flora of Western Siberia

AUTHORS : Kaminsky I.P. | Kadyrov T.V. | Ivanov V.V. | Belousov M.V.

RELEVANT UNIVERSITIES : Federal State Budgetary Educational Institution of Higher Education “Siberian State Medical University” of the Ministry of Health of the Russian Federation, Tomsk
YEAR : 2019

 

SUMMARY In experiments on golden male hamsters, the anti-opisthorchiasis activity (against Opisthorchis
felineus) of extracts obtained from Centaurea scabiosa L., Centaurea pseudomaculosa Dobrocz., Centaurea jaceae L. and Centaurea phrygia L. of the Asteraceae family was studied. The presence of anti-opisthorchiasis activity was confirmed in the sesquiterpene lactone of the guaian type,
cinaropicrin, isolated from Centaurea scabiosa L. It was suggested that the sesquiterpene lactones
grosshemin and repin have anti-opisthorchiasis activity.

 

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