To the pharmacology of “St. John’s herb” (Hypericum perforatum – Hypericum perforatum). First message
AUTHORS : Barnaulov O.D. | Bekhtereva N.P.
RELEVANT UNIVERSITIES : Institute of the Human Brain, Russian Academy of Sciences, St. Petersburg
YEAR : 2015
SUMMARY Summarizing the information on the use of the aerial part of St. John’s wort in a number of diseases and syndromes of a neurological profile, as well as in epilepsy, the effect of its infusion, the flavonoids of hyperoside, quercetin, kaempferol, rutin isolated from it, the amount of flavonoids on convulsions caused
by corazole, strychnine, thiosomalis and maximum electric shock (MES). Having established the absence of anticonvulsant properties of phytopreparations in
comparison with the once injected classical anticonvulsants seduxen and depakin, a moderate increase in tolerance to corazole, thiosemicarbazide and MES was
recorded against the background of a course, but not a single dose of St. John’s
wort infusion.
