Immunostimulating activity of triterpene glycosides in Saponaria roots officinalis L
AUTHORS : Edelev1 YES. | Kuznetsova2 T.A. | Ivanushko2 L.A. | Yudina2 T.P. | Frolova2 G.M. | Cherevach3 E.I. | Novak2 S.A.
RELEVANT UNIVERSITIES : 1FSBEI HPE “Moscow State University of Food Production”, g.
Moscow, 2FSBI “Research Institute of Epidemiology and Microbiology” SB RAMS, Vladivostok,
3FGAOU VPO “Far Eastern Federal University”, Vladivostok
YEAR : 2012
SUMMARY The effect of triterpene glycosides of Saponaria officinalis L. roots on the synthesis of cytokines INFγ, TNFα, IL-1ß, IL-6, IL-4 by human mononuclear cells in vitro was studied. Their dose-dependent immunomodulatory effect was established, aimed at stimulating cellular immunity, which suggests the possibility
of their use in the production of functional food products for the prevention of
immune diseases and prevention of food allergic reactions.
