Development and validation of a method for the quantitative determination of the amount of flavonoids in grass shepherd’s purse
AUTHORS : Evdokimova O.V.
RELEVANT UNIVERSITIES : GOU VPO First Moscow State Medical University named after I.M.Sechenov, St.
Moscow
YEAR : 2011
Nowaydays there isn’t any method for quantitative definition of biologically active substances in the normative documentation for Capsella bursa – pastoris (L.) Medik. materials. As the requirements for the crude drugs’ standardization increase steadily it is necessary to make a quantitative assessment of
biologically active substances. This study’s aim was to work out a method for Capsella bursa – pastoris (L.)
Medik. materials crude quantitative assessment and its subsequent validation. The research team devised
a method for Capsella bursa – pastoris materials active substances’ quantitative determination.
Application criteria for the accuracy, repeatability, reproducibility and linearity method were also
determined. This method for Capsella bursa – pastoris materials active substances’ quantitative
determination was to the validation of compendial method. A norm of biologically active substances’
content in nettle leaves was proposed. The results of the study were included in the normative
documentation for “Krasnogorskleksredstva” House monography.
