Investigation of the informativeness of the vegetative resonance test in dianosis of diseases of the inner ear and idiosyncrasy to aminoglycosides.

Investigation of the informativeness of the vegetative resonance test in dianosis of diseases of the inner ear and idiosyncrasy to aminoglycosides.

AUTHORS :  Abakarov M.G.|   Magomedov M.M.|  Makayev H.M.|  Khanakaeva Z.K.

RELEVANT UNIVERSITIES : Department of Clinical
Famacology, Federal State Institution of Higher Professional Education “Russian State Medical
University” of Roszdrav, Head Professor, Corresponding Member of RAMNYU.B.Belousov;
Department of Otolaryngology, Federal State Institution of Higher Professional Education “Russian State Medical
University” of Roszdrav, Head Professor, Corresponding Member of RAMS VT Palchun; ENT department of the
Federal State Institution “Moscow Research Institute of Pediatrics and Pediatric Surgery”; Moscow city,
Russia
YEAR : 2007

 

Currently, a large number of drugs are known that can cause damage to the auditory analyzer with a frequent outcome in irreversible sensorineural hearing
loss. The most studied drug sensorineural hearing loss caused by aminoglycosides, which, in accordance with modern concepts, develops by the mechanism of
idiosyncrasy as a result of genetic mutations, and drugs cause the phenotypic manifestation of these mutations (Fishel-Gotsian, 1998). After the identification of
the A1555G mutation in the 12S position of mitochondrial RNA in the United States, the issue of molecular genetic screening began to be discussed

 

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